Open AccessBaseline Level and Reduction in PaCO2 are Associated with the Treatment Effect of Long-Term Home Noninvasive Positive Pressure Ventilation in Stable Hypercapnic Patients with COPD: A Systematic Review and Meta-Analysis of Randomized Controlled Trials
Author(s) -
Zhipeng Wu,
Zujin Luo,
Zengtao Luo,
Jingyi Ge,
Jiawei Jin,
Zhixin Cao,
Yingmin Ma
Publication year - 2022
Publication title -
international journal of chronic obstructive pulmonary disease/international journal of copd
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.394
H-Index - 67
eISSN - 1178-2005
pISSN - 1176-9106
DOI - 10.2147/copd.s344962
Subject(s) - medicine , copd , meta analysis , confidence interval , ventilation (architecture) , relative risk , randomized controlled trial , subgroup analysis , mechanical ventilation , anesthesia , quality of life (healthcare) , mechanical engineering , nursing , engineering
The evidence of long-term home noninvasive positive pressure ventilation (LTHNIPPV) in patients with stable hypercapnic chronic obstructive pulmonary disease (COPD) is controversial. In this meta-analysis study, we sought to establish whether a baseline level and reduction in partial pressure of arterial carbon dioxide (PaCO2) were associated with the treatment effect of LTHNIPPV in these patients.