Open AccessAerobic Exercise Alleviates Inflammation, Oxidative Stress, and Apoptosis in Mice with Chronic Obstructive Pulmonary Disease
Author(s) -
Xishuai Wang,
Zhiqing Wang,
Donghui Tang
Publication year - 2021
Publication title -
international journal of chronic obstructive pulmonary disease/international journal of copd
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.394
H-Index - 67
eISSN - 1178-2005
pISSN - 1176-9106
DOI - 10.2147/copd.s309041
Subject(s) - medicine , bronchoalveolar lavage , oxidative stress , inflammation , nitrotyrosine , immunology , myeloperoxidase , endocrinology , pathology , lung , nitric oxide synthase , nitric oxide
Chronic inflammation, oxidative stress, and apoptosis play critical roles in chronic obstructive pulmonary disease (COPD) pathogenesis. Here, we attempted to determine whether aerobic exercise (AE) could improve COPD by counteracting the COPD-associated inflammatory response, oxidative stress, and apoptosis in mice.