Open AccessSputum Protein Biomarkers in Airway Diseases: A Pilot Study
Author(s) -
Angira Dasgupta,
Rahul Chakraborty,
Bodhisattwa Saha,
Himanshi Suri,
Praveen Singh,
Anurag Raj,
Bhupesh Taneja,
Debasis Dash,
Shantanu Sengupta,
Anurag Agrawal
Publication year - 2021
Publication title -
international journal of chronic obstructive pulmonary disease/international journal of copd
Language(s) - Uncategorized
Resource type - Journals
SCImago Journal Rank - 1.394
H-Index - 67
eISSN - 1178-2005
pISSN - 1176-9106
DOI - 10.2147/copd.s306035
Subject(s) - sputum , mucin , medicine , copd , chronic bronchitis , airway , asthma , mucus , respiratory tract , immunology , pathology , respiratory system , biology , tuberculosis , surgery , ecology
Chronic mucous hypersecretion (CMH or chronic bronchitis) per se or when associated with chronic inflammatory airway diseases such as asthma or chronic obstructive pulmonary disease (COPD) has several adverse clinical consequences. The sputum fluid phase has several candidate proteins including mucins which have the potential of being therapeutic targets, but has not yet been explored in-depth. This study aimed at exploring the profile of sputum proteins in various airway diseases.