Open AccessEicosanoids and Eosinophilic Inflammation of Airways in Stable COPD
Author(s) -
Natalia CelejewskaWójcik,
Aleksander Kania,
Karolina Górka,
Paweł Nadziakiewicz,
Krzysztof Wójcik,
Anna Gielicz,
Lucyna Mastalerz,
Marek Sanak,
Krzysztof Sładek
Publication year - 2021
Publication title -
international journal of chronic obstructive pulmonary disease/international journal of copd
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.394
H-Index - 67
eISSN - 1178-2005
pISSN - 1176-9106
DOI - 10.2147/copd.s298678
Subject(s) - copd , medicine , sputum , asthma , eosinophil , exhaled breath condensate , inflammation , eosinophilic , arachidonic acid , immunology , prostaglandin d2 , eosinophilia , gastroenterology , prostaglandin , pathology , biochemistry , chemistry , tuberculosis , enzyme
Lipid mediators, particularly eicosanoids, are associated with airway inflammation, especially with the eosinophilic influx. This study aimed to measure lipid mediators and cells in induced sputum, that could possibly reflect the inflammatory process in the bronchial tree of COPD subjects.