
High Blood Eosinophil and YKL-40 Levels, as Well as Low CXCL9 Levels, are Associated with Increased Readmission in Patients with Acute Exacerbation of Chronic Obstructive Pulmonary Disease
Author(s) -
Junnan Peng,
Qian Yu,
Shulei Fan,
Xingru Chen,
Rui Tang,
Daoxin Wang,
Di Qi
Publication year - 2021
Publication title -
international journal of chronic obstructive pulmonary disease/international journal of copd
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.394
H-Index - 67
eISSN - 1178-2005
pISSN - 1176-9106
DOI - 10.2147/copd.s294968
Subject(s) - medicine , copd , exacerbation , eosinophil , white blood cell , biomarker , blood test , periostin , odds ratio , gastroenterology , immunology , asthma , biochemistry , chemistry , extracellular matrix , biology , microbiology and biotechnology
Readmission after hospital discharge is common among patients with acute exacerbation of chronic obstructive pulmonary disease (AECOPD). Predictive biomarkers of readmission would facilitate stratification strategies and individualized prognosis. Therefore, this study aimed to investigate the utility of type 2 biomarkers (eosinophils, periostin, and YKL-40) and a type 1 biomarker (CXCL9) in predicting readmission events in patients with AECOPD.