Open Access<p>High-Flow Nasal Cannula for Chronic Obstructive Pulmonary Disease with Acute Compensated Hypercapnic Respiratory Failure: A Randomized, Controlled Trial</p>
Author(s) -
Xuyan Li,
Xiao Tang,
Rui Wang,
Yuan Xue,
Yingying Zhao,
Li Wang,
Haichao Li,
Huiwen Chu,
Jie Li,
Wenping Mao,
Yujun Wang,
Zhan-Hong Tian,
Jianhua Liu,
Qin Luo,
Bing Sun,
Zhaohui Tong
Publication year - 2020
Publication title -
international journal of chronic obstructive pulmonary disease/international journal of copd
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.394
H-Index - 67
eISSN - 1178-2005
pISSN - 1176-9106
DOI - 10.2147/copd.s283020
Subject(s) - medicine , nasal cannula , exacerbation , anesthesia , respiratory failure , oxygen therapy , acute exacerbation of chronic obstructive pulmonary disease , randomized controlled trial , copd , hypercapnia , clinical endpoint , cannula , respiratory system , surgery
Currently, there is a lack of evidence on the utilization of high-flow nasal cannula (HFNC) in patients with acute exacerbation of chronic obstructive pulmonary disease (AECOPD) accompanied by hypercapnic respiratory failure. We aimed to explore the efficacy and safety of HFNC compared with conventional oxygen therapy (COT) in such patients.