Open AccessWhen to Use Initial Triple Therapy in COPD: Adding a LAMA to ICS/LABA by Clinically Important Deterioration Assessment
Author(s) -
Wan-Ju Cheng,
BiingRu Wu,
WeiChih Liao,
Chih-Yu Chen,
WeiChun Chen,
TeChun Hsia,
ChihYen Tu,
Chia-Hung Chen,
WuHuei Hsu
Publication year - 2020
Publication title -
international journal of chronic obstructive pulmonary disease/international journal of copd
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.394
H-Index - 67
eISSN - 1178-2005
pISSN - 1176-9106
DOI - 10.2147/copd.s279482
Subject(s) - lama , medicine , copd , intensive care medicine
Triple therapy versus dual therapy for chronic pulmonary obstructive disease (COPD) can reduce symptoms, limit the risk of acute exacerbations (AEs) as well as improve lung function. Currently, studies that feature clinically important deterioration (CID) as a composite endpoint to assess the need for treatment intensification for patients maintained on dual therapy remained to be scarce.