Open Access<p>Impact of Combined Chronic Obstructive Pulmonary Disease Status and Systemic Inflammation on Outcome of Advanced NSCLC: Multicenter Retrospective Cohort Study</p>
Author(s) -
Jeong Uk Lim,
Hye Seon Kang,
Chang Dong Yeo,
Ju Sang Kim,
Chan Kwon Park,
Yong Hyun Kim,
Jin Woo Kim,
Seung Joon Kim,
Sang Haak Lee
Publication year - 2020
Publication title -
international journal of chronic obstructive pulmonary disease/international journal of copd
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.394
H-Index - 67
eISSN - 1178-2005
pISSN - 1176-9106
DOI - 10.2147/copd.s274354
Subject(s) - medicine , systemic inflammation , pulmonary disease , retrospective cohort study , cohort study , copd , cohort , inflammation , oncology
In patients with non-small cell lung cancer (NSCLC), both chronic obstructive pulmonary disease (COPD) and systemic inflammatory biomarkers, such as neutrophil-lymphocyte ratio (NLR) and platelet-lymphocyte ratio (PLR), have significant association with prognosis. NLR and PLR also predict mortality in patients with COPD alone. A combination of the two parameters may be helpful in a more individualized approach for predicting prognosis in NSCLC.