Open Access<p>Comorbidity Associations with AATD Among Commercially Insured and Medicare Beneficiaries with COPD in the US</p>
Author(s) -
Robert A. Sandhaus,
Charlie Strange,
Glenda Stone,
M. Chris Runken,
Christopher M. Blanchette,
Reuben Howden
Publication year - 2020
Publication title -
international journal of chronic obstructive pulmonary disease/international journal of copd
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.394
H-Index - 67
eISSN - 1178-2005
pISSN - 1176-9106
DOI - 10.2147/copd.s263297
Subject(s) - medicine , copd , comorbidity , cohort , chronic liver disease , alpha 1 antitrypsin deficiency , logistic regression , disease , pulmonary disease , liver disease , cohort study , cirrhosis
Alpha-1 antitrypsin deficiency (AATD) is often not identified in patients with chronic obstructive pulmonary disease (COPD) until advanced stages of disease, despite the availability of genetic testing. While clinical practice guidelines provide recommendations on patients who should be tested, more refined algorithms are needed to identify COPD patients who are likely candidates for AATD testing and to prevent delays in diagnosis and treatment. The objective of this study was to identify comorbid associations with AATD among patients diagnosed with COPD in the United States.