Open Access<p>Construction of Potential miRNA–mRNA Regulatory Network in COPD Plasma by Bioinformatics Analysis</p>
Author(s) -
Mengchan Zhu,
Maosong Ye,
Jian Wang,
Ling Ye,
Meiling Jin
Publication year - 2020
Publication title -
international journal of chronic obstructive pulmonary disease/international journal of copd
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.394
H-Index - 67
eISSN - 1178-2005
pISSN - 1176-9106
DOI - 10.2147/copd.s255262
Subject(s) - microrna , kegg , gene , microarray , microarray analysis techniques , copd , foxo3 , downregulation and upregulation , pi3k/akt/mtor pathway , bioinformatics , gene regulatory network , biology , candidate gene , computational biology , medicine , gene expression , signal transduction , genetics , gene ontology
Chronic obstructive pulmonary disease (COPD) has become a major cause of morbidity and mortality worldwide. Increasing evidence indicates that aberrantly expressed microRNAs (miRNAs) are involved in the pathogenesis of COPD. However, an integrative exploration of miRNA-mRNA regulatory network in COPD plasma remains lacking.