Open Access<p>Th1/Th17 Cytokine Profiles are Associated with Disease Severity and Exacerbation Frequency in COPD Patients</p>
Author(s) -
Yan Yu,
Lili Zhao,
Yong Xie,
Yu Xu,
Weike Jiao,
Jianhui Wu,
Xinyu Deng,
Guiju Fang,
Qing Xue,
Yali Zheng,
Zhancheng Gao
Publication year - 2020
Publication title -
international journal of chronic obstructive pulmonary disease/international journal of copd
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.394
H-Index - 67
eISSN - 1178-2005
pISSN - 1176-9106
DOI - 10.2147/copd.s252097
Subject(s) - medicine , exacerbation , copd , sputum , cytokine , pathogenesis , copd exacerbation , gastroenterology , immunology , pathophysiology , acute exacerbation of chronic obstructive pulmonary disease , pathology , tuberculosis
T helper (Th) cell cytokine imbalances have been associated with the pathophysiology of chronic obstructive pulmonary disease (COPD), including the Th1/Th2 and Th17/T regulatory cells (Treg) paradigms. Clarifying cytokine profiles during COPD acute exacerbation (AE) and their relationships with clinical manifestations would help in understanding the pathogenesis of disease and improve clinical management.