Open Access<p>Necroptosis Mediates Cigarette Smoke-Induced Inflammatory Responses in Macrophages</p>
Author(s) -
Yong Wang,
Xiaoke Wang,
Peipei Wu,
Yi Wang,
Lixuan Ren,
XU Ai-hui
Publication year - 2020
Publication title -
international journal of chronic obstructive pulmonary disease/international journal of copd
Language(s) - Uncategorized
Resource type - Journals
SCImago Journal Rank - 1.394
H-Index - 67
eISSN - 1178-2005
pISSN - 1176-9106
DOI - 10.2147/copd.s233506
Subject(s) - necroptosis , inflammation , medicine , tumor necrosis factor alpha , chemokine , proinflammatory cytokine , immunology , cytokine , ripk1 , programmed cell death , cancer research , apoptosis , biology , biochemistry
Cigarette smoke (CS)-induced inflammation in macrophages is involved in the pathological process of chronic obstructive pulmonary disease (COPD). Necroptosis, which is a form of programmed necrosis, has a close relationship with robust inflammation, while its roles in COPD are unclear.