Open Access<p>Mixed Phenotype of Emphysema and Airway Wall Thickening Is Associated with Frequent Exacerbation in Chronic Obstructive Pulmonary Disease Patients</p>
Author(s) -
Jeong Uk Lim,
Eun Kyung Kim,
Seong Yong Lim,
Jin Hwa Lee,
Jae Seung Lee,
SangDo Lee,
Yeon Mok Oh,
Chin Kook Rhee
Publication year - 2019
Publication title -
international journal of chronic obstructive pulmonary disease/international journal of copd
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.394
H-Index - 67
eISSN - 1178-2005
pISSN - 1176-9106
DOI - 10.2147/copd.s227377
Subject(s) - medicine , copd , exacerbation , univariate analysis , phenotype , gastroenterology , airway , obstructive lung disease , lung , pathology , multivariate analysis , surgery , biochemistry , chemistry , gene
The presence of both emphysema and airway wall thickening determined via volumetric computed tomography (CT) is defined as mixed phenotype. The long-term clinical course of this phenotype has not been studied in depth. This study compared the mixed phenotype to other phenotypes of chronic obstructive pulmonary disease (COPD) patients.