Open Access<p>Comparative Effectiveness Of Fluoroquinolone Antibiotic Use In Uncomplicated Acute Exacerbations Of COPD: A Multi-Cohort Study</p>
Author(s) -
Pierre Ernst,
Matthew Dahl,
Dan Château,
Nick Daneman,
Jacqueline M. Quail,
Ingrid Sketris,
Anat Fisher,
Jianguo Zhang,
Shawn Bugden
Publication year - 2019
Publication title -
international journal of chronic obstructive pulmonary disease/international journal of copd
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.394
H-Index - 67
eISSN - 1178-2005
pISSN - 1176-9106
DOI - 10.2147/copd.s226324
Subject(s) - medicine , levofloxacin , copd , antibiotics , medical prescription , moxifloxacin , ambulatory , cohort , retrospective cohort study , cohort study , exacerbation , propensity score matching , intensive care medicine , pharmacology , microbiology and biotechnology , biology
Fluoroquinolone antibiotics are associated with rare, but severe adverse events. They are frequently used for the treatment of acute exacerbations of COPD (AECOPD). While their effectiveness in severe exacerbations requiring hospitalisation has been well documented, the potential benefit in the ambulatory setting is less clear, especially in uncomplicated patients with COPD.