Open Access<p>Quantitative CT analysis in patients with pulmonary emphysema: is lung function influenced by concomitant unspecific pulmonary fibrosis?</p>
Author(s) -
Felix Feldhaus,
Dorothea Theilig,
R Hübner,
Jan-Martin Kuhnigk,
Konrad Neumann,
Felix Doellinger
Publication year - 2019
Publication title -
international journal of chronic obstructive pulmonary disease/international journal of copd
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.394
H-Index - 67
eISSN - 1178-2005
pISSN - 1176-9106
DOI - 10.2147/copd.s204007
Subject(s) - medicine , copd , pulmonary function testing , concomitant , parenchyma , lung , lung volumes , dlco , vital capacity , pulmonary fibrosis , respiratory disease , fibrosis , cardiology , pathology , gastroenterology , lung function , diffusing capacity
Quantitative analysis of CT scans has proven to be a reproducible technique, which might help to understand the pathophysiology of chronic obstructive pulmonary disease (COPD) and combined pulmonary fibrosis and emphysema. The aim of this retrospective study was to find out if the lung function of patients with COPD with Global Initiative for Chronic Obstructive Lung Disease (GOLD) stages III or IV and pulmonary emphysema is measurably influenced by high attenuation areas as a correlate of concomitant unspecific fibrotic changes of lung parenchyma.