Open AccessDownregulated lncRNA SNHG18 Suppresses the Progression of Hepatitis B Virus-Associated Hepatocellular Carcinoma and Meditates the Antitumor Effect of Oleanolic Acid
Author(s) -
Wenqi Song,
Xuemei Zhang,
Feng Li,
Yongwei Lai,
Tongtong Li,
Pengxia Zhang
Publication year - 2022
Publication title -
cancer management and research
Language(s) - English
Resource type - Journals
ISSN - 1179-1322
DOI - 10.2147/cmar.s346920
Subject(s) - hepatocellular carcinoma , hepatitis b virus , medicine , cancer research , oleanolic acid , biomarker , downregulation and upregulation , hepatitis b , transfection , immunology , virus , cell culture , pathology , chemistry , biology , gene , biochemistry , alternative medicine , genetics
Oleanolic acid (OA) has been widely reported to possess antitumor effects, but the specific molecular mechanism underlying its inhibition of hepatocellular carcinoma (HCC) progression remains unclear. This study aims to uncover the mechanism of OA antitumor effect on HBV-associated HCC and identify a potential biomarker for tumor progression.