Open AccessIs the Fixed Periodic Treatment Effective for the Tumor System without Complete Information?
Author(s) -
Jiali Wang,
Yixuan Zhang,
Xiaoquan Liu,
Haochen Liu
Publication year - 2021
Publication title -
cancer management and research
Language(s) - English
Resource type - Journals
ISSN - 1179-1322
DOI - 10.2147/cmar.s339787
Subject(s) - population , nonlinear system , computer science , process (computing) , control theory (sociology) , mathematics , medicine , artificial intelligence , control (management) , physics , environmental health , quantum mechanics , operating system
The treatment plans designed with the guidance of the mathematical model and adaptive strategy can trap tumor subpopulations in a periodic and controllable loop. But this process requires detailed information about the tumor system, which is difficult to obtain. Therefore, we wondered whether the fixed periodic treatment plans designed with the typical values of population parameters could be applied to a similar tumor system without complete information.