Open AccessSOX10 Knockdown Inhibits Melanoma Cell Proliferation via Notch Signaling Pathway
Author(s) -
Youqun Tang,
Yanming Cao
Publication year - 2021
Publication title -
cancer management and research
Language(s) - Uncategorized
Resource type - Journals
ISSN - 1179-1322
DOI - 10.2147/cmar.s329331
Subject(s) - sox10 , gene knockdown , notch signaling pathway , melanoma , cancer research , signal transduction , biology , ectopic expression , microphthalmia associated transcription factor , transcription factor , microbiology and biotechnology , apoptosis , cell culture , gene , genetics
Melanoma is a serious and malignant disease worldwide. Seeking diagnostic markers and potential therapeutic targets is urgent for melanoma treatment. SOX10, a member of the SoxE family of genes, is a transcription factor which can regulate the transcription of a wide variety of genes in multiple cellular processes.