Open AccessIdentification of Prognostic Biomarkers Among FAM83 Family Genes in Human Ovarian Cancer Through Bioinformatic Analysis and Experimental Verification
Author(s) -
Shaochong Lin,
Junpeng Du,
Jun Hao,
Xinrong Luo,
Han Wu,
Huifang Zhang,
Xinxin Zhao,
Libin Xu,
Bao-Jin Wang
Publication year - 2021
Publication title -
cancer management and research
Language(s) - English
Resource type - Journals
ISSN - 1179-1322
DOI - 10.2147/cmar.s328851
Subject(s) - ovarian cancer , gene , biology , survival analysis , downregulation and upregulation , cancer research , cell cycle , oncology , oncogene , cancer , immunohistochemistry , medicine , bioinformatics , microarray , microarray analysis techniques , gene expression , genetics
Family with sequence similarity 83 (FAM83) is a newly discovered oncogene family, and the members of which can affect the prognosis of patients with malignant tumors via various mechanisms. However, the functions and molecular mechanisms of FAM83 genes in ovarian cancer (OC) have not yet been investigated. This study aimed to explore the clinical significance and prognostic value of FAM83 genes in OC.