Open AccessPrognostic Value of an m5C RNA Methylation Regulator-Related Signature for Clear Cell Renal Cell Carcinoma
Author(s) -
Hanrong Li,
Huiming Jiang,
Zhicheng Huang,
Zhilin Chen,
Nanhui Chen
Publication year - 2021
Publication title -
cancer management and research
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.024
H-Index - 40
ISSN - 1179-1322
DOI - 10.2147/cmar.s323072
Subject(s) - clear cell renal cell carcinoma , methylation , rna methylation , dna methylation , biology , kidney cancer , rna , cancer , cancer research , renal cell carcinoma , oncology , gene expression , gene , medicine , genetics , methyltransferase
Clear cell renal cell carcinoma (ccRCC) is highly heterogeneous and is one of the most lethal types of cancer within the urinary system. Aberrant expression of 5-methylcytosine (m 5 C) RNA methylation regulators has been shown to result in occurrence and progression of tumors. However, the role of these regulators in ccRCC remains unclear.