Open AccessExplore the Value of Adding Induction Chemotherapy to Concurrent Chemoradiotherapy in T3-4N0M0 Nasopharyngeal Carcinoma Patients: A Retrospective Study
Author(s) -
Peijing Li,
Qun Zhang,
Dong-Hua Luo,
Feng Jiang,
Jin Qi,
Hua Ye,
Tengchuan Jin,
Xiaozhong Chen
Publication year - 2021
Publication title -
cancer management and research
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.024
H-Index - 40
ISSN - 1179-1322
DOI - 10.2147/cmar.s321471
Subject(s) - medicine , nasopharyngeal carcinoma , induction chemotherapy , oncology , chemoradiotherapy , stage (stratigraphy) , multivariate analysis , retrospective cohort study , chemotherapy , population , radiation therapy , paleontology , environmental health , biology
Patients with T3-4N0M0 nasopharyngeal carcinoma (NPC) are a unique subgroup of locoregional advanced NPC, which generally have a better prognosis than others and are often excluded in most randomized controlled clinical trials focusing on locoregional advanced NPC. The management of this population is still controversial. This study aims to evaluate the outcomes of T3-4N0M0 NPC patients treated with sequential induction chemotherapy and concurrent chemoradiotherapy (IC+CCRT) or chemoradiotherapy (CCRT) alone.