Open AccessThe Role and Application of Salivary Exosomes in Malignant Neoplasms
Author(s) -
Yongqin Deng,
Yujie Cao,
Liuqian Wang,
Dong Ye
Publication year - 2021
Publication title -
cancer management and research
Language(s) - English
Resource type - Journals
ISSN - 1179-1322
DOI - 10.2147/cmar.s321225
Subject(s) - microvesicles , exosome , medicine , liquid biopsy , cancer research , saliva , salivary gland , cancer , pathology , microrna , biology , gene , biochemistry
The study of salivary exosomes in malignant neoplasms has attracted widespread attention in the clinical setting. Although a variety of diagnostic and treatment approaches have been proposed, there are some limitations to their application. In recent years, the role of salivary exosomes in cancer has been increasingly studied. Salivary exosomes not only renew and regulate the biological behavior of tumor cells, such as malignant proliferation, migration, and invasion, but they also serve as ideal markers for early diagnosis of diseases and may represent an effective therapeutic target. This article reviews the current research on salivary exosomes in malignant neoplasms.