Open AccessLncRNA DNAJC3-AS1 Promotes Hepatocellular Carcinoma (HCC) Progression via Sponging Premature miR-27b
Author(s) -
Changbo Fu,
Jianxiu Li,
Ping Li,
Dan Cheng
Publication year - 2021
Publication title -
cancer management and research
Language(s) - Uncategorized
Resource type - Journals
SCImago Journal Rank - 1.024
H-Index - 40
ISSN - 1179-1322
DOI - 10.2147/cmar.s321111
Subject(s) - gene knockdown , downregulation and upregulation , cancer research , long non coding rna , hepatocellular carcinoma , microrna , antisense rna , cell growth , biology , tumor progression , rna , cell culture , cancer , gene , genetics , biochemistry
Long non-coding RNA (lncRNA) DNAJC3 antisense RNA 1 (head to head) (DNAJC3-AS1) plays a key role in the progression of several cancers. However, its biological role in hepatocellular carcinoma (HCC) is still unclear. We aimed to investigate the role of DNAJC3-AS1 in the development of HCC and reveal the potential mechanisms.