Open AccessHigh-Expression of Cytoplasmic Poly (A) Binding Protein 1 (PABPC1) as a Prognostic Biomarker for Early-Stage Esophageal Squamous Cell Carcinoma
Author(s) -
Jiangtao Pu,
Tao Zhang,
Dengguo Zhang,
Kaiming He,
Yonghong Chen,
Xingwang Sun,
Wenbo Long
Publication year - 2021
Publication title -
cancer management and research
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.024
H-Index - 40
ISSN - 1179-1322
DOI - 10.2147/cmar.s317631
Subject(s) - cancer research , immunohistochemistry , biology , tissue microarray , microbiology and biotechnology , oncology , medicine
Poly (A) binding protein cytoplasmic 1 (PABPC1) plays a crucial role in the regulation of RNA polyadenylation, translation initiation, and mRNA stability and may be involved in tumorigenesis. Herein, we set out to identify the prognostic value of PABPC1 expression in esophageal squamous cell carcinoma (ESCC).