Open AccessAnalysis of Factors Related to Lymph Node Metastasis in Early-Stage Type 1 Endometrial Cancer: Verifying the Clinical Value of Positive Threshold of the Immunohistochemical Parameter Ki67
Author(s) -
Peng Jiang,
Rui Yuan
Publication year - 2021
Publication title -
cancer management and research
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.024
H-Index - 40
ISSN - 1179-1322
DOI - 10.2147/cmar.s316211
Subject(s) - youden's j statistic , receiver operating characteristic , medicine , stage (stratigraphy) , endometrial cancer , multivariate analysis , univariate , oncology , immunohistochemistry , univariate analysis , cancer , gastroenterology , multivariate statistics , statistics , mathematics , biology , paleontology
Lymph node metastasis (LNM) is an important reference indicator for the prognosis of endometrial cancer (EC). Even in patients with early low-risk EC, many people still have LNM. The purpose of this study was to investigate the related factors influencing LNM in early-stage EC and determine the optimal positive threshold of immunohistochemical parameter Ki67 for predicting LNM, providing auxiliary reference indicators for clinical diagnosis and treatment.