Open AccesscircTADA2A Retards the Progression of Colorectal Cancer via Regulating miR-1229/BCL2L10 Signal Axis
Author(s) -
Li Hu,
Lei Fang,
Zhiping Zhang,
Zhilong Yan
Publication year - 2021
Publication title -
cancer management and research
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.024
H-Index - 40
ISSN - 1179-1322
DOI - 10.2147/cmar.s314548
Subject(s) - colorectal cancer , microrna , cancer research , cell growth , cancer , suppressor , luciferase , western blot , biology , apoptosis , cell culture , transfection , genetics , gene
Colorectal cancer (CRC) is one of the leading causes of cancer-related death around the world, becoming a severe public health problem. Mounting evidence has proven that circRNAs act as pivotal modulators in the initiation and development of CRC. Although the function of circTADA2A has been explored in osteosarcoma and breast cancer, the specific role of circTADA2A in CRC remains unknown.