Open AccessIdentification of ZNF704 as a Novel Oncogene and an Independent Prognostic Marker in Chondrosarcoma
Author(s) -
Changbao Chen,
Hua Zhou,
Xiaolin Zhang,
Zhongjun Liu,
Xiaofang Ma
Publication year - 2021
Publication title -
cancer management and research
Language(s) - English
Resource type - Journals
ISSN - 1179-1322
DOI - 10.2147/cmar.s313229
Subject(s) - chondrosarcoma , oncogene , gene knockdown , immunohistochemistry , cancer research , biology , carcinogenesis , pathology , apoptosis , cartilage , medicine , cell cycle , cancer , biochemistry , anatomy
The transcription factor zinc finger protein 704 (ZNF704) is implicated in tumorigenesis. However, the underlying role of ZNF704 in the pathogenesis of chondrosarcoma remains not well delineated. This study investigates the expression level, prognostic significance and potential biological function of ZNF704 in human chondrosarcoma.