Open AccessPrognostic Significance of Serum PD-L1 Level in Patients with Locally Advanced or Metastatic Esophageal Squamous Cell Carcinoma Treated with Combination Cytotoxic Chemotherapy
Author(s) -
Rong Fu,
Chuanqing Jing,
Xiurong Li,
Zhaofeng Tan,
Huijie Li
Publication year - 2021
Publication title -
cancer management and research
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.024
H-Index - 40
ISSN - 1179-1322
DOI - 10.2147/cmar.s312690
Subject(s) - medicine , oncology , chemotherapy , biomarker , esophageal squamous cell carcinoma , immunohistochemistry , cytotoxic t cell , confounding , carcinoma , biology , biochemistry , in vitro
There are no useful biomarkers for the clinical outcome of advanced esophageal squamous cell carcinoma (ESCC). In this study, we aimed to investigate the prognostic value of soluble PD-L1 (sPD-L1) in serum of patients with locally advanced or metastatic ESCC who received cytotoxic chemotherapy as first-line treatment.