Open AccessHuman Polycomb Protein 2 (hPC2) as a Novel Independent Prognostic Marker in Nasopharyngeal Carcinoma
Author(s) -
Mingmin Wu,
Li Yang,
Xiaojuan Hou,
Ziyuan Wang,
Jianqing Zhang
Publication year - 2021
Publication title -
cancer management and research
Language(s) - English
Resource type - Journals
ISSN - 1179-1322
DOI - 10.2147/cmar.s308884
Subject(s) - nasopharyngeal carcinoma , medicine , hazard ratio , proportional hazards model , survival analysis , immunohistochemistry , stage (stratigraphy) , confidence interval , gastroenterology , oncology , endocrinology , biology , radiation therapy , paleontology
Human polycomb protein 2(hPC2) is a vital component of polycomb repressive complex 1(PRC1). It plays a critical role in tumorigenesis and progression. However, whether HPC2 expression affects the prognosis of patients with nasopharyngeal carcinoma (NPC) is currently unclear. In the present study, we investigated the expression of hPC2and elucidated its clinical prognostic significance in NPC.