Open AccessPerioperative Safety and Effectiveness of Neoadjuvant Therapy with Fluorouracil, Leucovorin, Oxaliplatin, and Docetaxel Plus Apatinib in Locally Advanced Gastric Cancer
Author(s) -
Yonglei Zhang,
Bin Zhang,
Jiong Yang,
Jindai Zhang,
Wei Zhang
Publication year - 2021
Publication title -
cancer management and research
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.024
H-Index - 40
ISSN - 1179-1322
DOI - 10.2147/cmar.s304093
Subject(s) - apatinib , docetaxel , medicine , oxaliplatin , oncology , neoadjuvant therapy , perioperative , cancer , chemotherapy , stage (stratigraphy) , gastroenterology , colorectal cancer , surgery , breast cancer , paleontology , biology
The trend in neoadjuvant therapy for locally advanced gastric cancer (LAGC) is to use more drugs or therapies in combination. This study aimed to assess the safety and effectiveness of neoadjuvant chemotherapy with fluorouracil, leucovorin, oxaliplatin, and docetaxel (FLOT) plus apatinib in the treatment of LAGC.