Open AccessNormal Basal Epithelial Cells Stimulate the Migration and Invasion of Prostate Cancer Cell RM-1 by TGF-β1/STAT3 Axis in vitro
Author(s) -
Chunyan Li,
Chen Chun-ya,
Jian-Hong An,
Jianbin Wu,
Hong Shen
Publication year - 2021
Publication title -
cancer management and research
Language(s) - English
Resource type - Journals
ISSN - 1179-1322
DOI - 10.2147/cmar.s303122
Subject(s) - prostate cancer , gentamicin protection assay , cell migration , basal (medicine) , cancer research , vimentin , cancer cell , chemistry , epithelial–mesenchymal transition , immunocytochemistry , cell , microbiology and biotechnology , biology , cancer , pathology , metastasis , immunohistochemistry , medicine , endocrinology , biochemistry , insulin
Basal epithelial cells are absent in distant prostate cancer. This study aimed to investigate whether basal epithelial cells could suppress migration and invasion of prostate cancer cells to become a new treatment strategy for prostate cancer.