Open AccessAnalysis of Mono-ADP-Ribosylation Levels in Human Colorectal Cancer
Author(s) -
ChuanLing Wang,
Yi Tang,
Ming Li,
Ming Xiao,
Qingshu Li,
Lian Yang,
Xian Li,
Yin Liu,
Yalan Wang
Publication year - 2021
Publication title -
cancer management and research
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.024
H-Index - 40
ISSN - 1179-1322
DOI - 10.2147/cmar.s303064
Subject(s) - colorectal cancer , medicine , cancer , immunohistochemistry , mouse model of colorectal and intestinal cancer , oncology , pathological , cancer research , adenocarcinoma , epigenetics , adp ribosylation , biology , gene , genetics , nad+ kinase , biochemistry , enzyme
Colorectal cancer remains a major public health problem with high morbidity and mortality rates. In the search for the mechanisms of colorectal cancer occurrence and development, increasing attention has been focused on epigenetics. The overall level of Mono-ADP-ribosylation, an epigenetic, has not been investigated now. The aim of our study was to analysis of the overall level of mono-ADP-ribosylation in colorectal cancer.