Open AccessCirc_0001944 Contributes to Glycolysis and Tumor Growth by Upregulating NFAT5 Through Acting as a Decoy for miR-142-5p in Non-Small Cell Lung Cancer
Author(s) -
Yawei Dou,
Wei Tian,
Hongtao Wang,
Shanshan Lv
Publication year - 2021
Publication title -
cancer management and research
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.024
H-Index - 40
ISSN - 1179-1322
DOI - 10.2147/cmar.s302814
Subject(s) - gene silencing , cancer research , gene knockdown , downregulation and upregulation , carcinogenesis , cell growth , microrna , lung cancer , chemistry , glycolysis , microbiology and biotechnology , biology , oncology , medicine , apoptosis , gene , metabolism , biochemistry
Circular RNAs (circRNAs) participate in the tumorigenesis of various cancers. CircRNA hsa_circ_0001944 (circ_0001944), derived from the TCONS_l2_00030860 gene, has been uncovered to be upregulated in NSCLC (non-small cell lung cancer). Nevertheless, the influence of circ_0001944 on glycolysis and tumor growth in NSCLC is unclear.