Open AccessAdenocarcinoma of High-Grade Patterns Associated with Distinct Outcome of First-Line Chemotherapy or EGFR-TKIs in Patients of Relapsed Lung Cancer
Author(s) -
Xiaofei Yu,
Zhengwei Dong,
Wanying Wang,
Shiqi Mao,
Yingying Pan,
Yiwei Liu,
Shuo Yang,
Bin Chen,
Chunyan Wang,
Xuefei Li,
Chao Zhao,
Keyi Jia,
ChaoPeng Shao,
Chunyan Wu,
Shengxiang Ren,
Caicun Zhou
Publication year - 2021
Publication title -
cancer management and research
Language(s) - English
Resource type - Journals
ISSN - 1179-1322
DOI - 10.2147/cmar.s302545
Subject(s) - medicine , adenocarcinoma , oncology , chemotherapy , lung cancer , stage (stratigraphy) , epidermal growth factor receptor , lung , cancer , gastroenterology , biology , paleontology
High-grade patterns (micropapillary/solid/complex gland) are associated with a higher recurrence rate and shorter disease-free survival. Thus far, it remains unclear whether the efficacy of first-line anticancer therapy is different from that of the other adenocarcinoma subgroups for patients with high-grade patterns. The study aimed to investigate the association between an adenocarcinoma with high-grade patterns with the outcomes of first-line treatment in patients with lung cancer.