Open AccessGrape Seed Proanthocyanidins (GSPs) Inhibit the Development of Cutaneous Squamous Cell Carcinoma by Regulating the hsa_circ_0070934/miR-136-5p/PRAF2 Axis
Author(s) -
Weibiao Xiong,
Lan’e Wu,
Runke Tang,
Qingqing Zhang,
Qin Guo,
Shuguang Song
Publication year - 2021
Publication title -
cancer management and research
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.024
H-Index - 40
ISSN - 1179-1322
DOI - 10.2147/cmar.s302084
Subject(s) - cell growth , flow cytometry , cancer research , apoptosis , cell cycle , viability assay , ectopic expression , microrna , western blot , cell , cell migration , biology , microbiology and biotechnology , chemistry , cell culture , biochemistry , genetics , gene
Grape seed proanthocyanidins (GSPs) have been shown to inhibit the progression of many cancers, including cutaneous squamous cell carcinoma (CSCC). Circular RNA (circRNA) is a key regulator for cancer progression. However, it is unclear whether GSPs can mediate the progression of CSCC by regulating circRNA.