Open AccessPotential Effects of the FLT3-ITD Mutation on Chemotherapy Response and Prognosis of Acute Promyelocytic Leukemia
Author(s) -
Yu-Hua Song,
Peng Peng,
Chun Qiao,
Jianyong Li,
Qi Long,
Hua Lu
Publication year - 2021
Publication title -
cancer management and research
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.024
H-Index - 40
ISSN - 1179-1322
DOI - 10.2147/cmar.s297421
Subject(s) - acute promyelocytic leukemia , medicine , arsenic trioxide , mutation , gastroenterology , white blood cell , leukemia , oncology , survival rate , chemotherapy , retinoic acid , biology , genetics , gene , apoptosis
To evaluate the influence of FLT3-ITD mutations on the treatment response and long-term survival of newly-diagnosed patients with acute promyelocytic leukemia (APL) treated with all-trans retinoic acid and arsenic trioxide.