Open AccessLong Non-Coding RNA TRIM52-AS1 Promotes Growth and Metastasis via miR-218-5p/ROBO1 in Hepatocellular Carcinoma
Author(s) -
Yuanjun Liu,
Yuzhang Wu,
Shuang Liu,
Yi Dai
Publication year - 2021
Publication title -
cancer management and research
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.024
H-Index - 40
ISSN - 1179-1322
DOI - 10.2147/cmar.s286205
Subject(s) - hepatocellular carcinoma , gene knockdown , metastasis , cancer research , competing endogenous rna , cell growth , antisense rna , long non coding rna , cell culture , clone (java method) , biology , rna , medicine , cancer , gene , biochemistry , genetics
Hepatocellular carcinoma (HCC) is a malignant disease with a high mortality among primary HCC patients worldwide. Lots of studies have shown that lncRNAs are known as the biomarkers in diagnosis, treatment and prognosis of hepatocellular carcinoma. Therefore, clarifying the detailed function and mechanism of the lncRNA in the HCC progressing seems particularly important.