Open AccessCircRNA hsa_circ_0005909 Promotes Cell Proliferation of Osteosarcoma Cells by Targeting miR-338-3p/HMGA1 Axis
Author(s) -
Cailong Zhang,
Li Liu,
Yingzhu Qiu
Publication year - 2021
Publication title -
cancer management and research
Language(s) - English
Resource type - Journals
ISSN - 1179-1322
DOI - 10.2147/cmar.s285118
Subject(s) - gene knockdown , downregulation and upregulation , cell growth , mapk/erk pathway , osteosarcoma , pi3k/akt/mtor pathway , protein kinase b , cancer research , microrna , clone (java method) , transfection , chemistry , cell culture , luciferase , microbiology and biotechnology , signal transduction , biology , gene , biochemistry , genetics
Osteosarcoma (OS) is the most common malignant bone tumor in the pediatric population. The main goal of this study is to investigate the role of hsa_circ_0005909 and the underlying signaling pathway involved in OS.