Open AccessKnockdown of SLC39A4 Expression Inhibits the Proliferation and Motility of Gallbladder Cancer Cells and Tumor Formation in Nude Mice
Author(s) -
Min Li,
Kun Fan,
Zheng Bao,
David Zekria,
Tao Suo,
Han Liu,
Sheng Shen,
Houbao Liu,
Xiaoling Ni
Publication year - 2021
Publication title -
cancer management and research
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.024
H-Index - 40
ISSN - 1179-1322
DOI - 10.2147/cmar.s282269
Subject(s) - cancer research , motility , cell growth , gallbladder cancer , gene knockdown , nude mouse , cell migration , viability assay , metastasis , mtt assay , apoptosis , biology , cancer , cell culture , microbiology and biotechnology , genetics , biochemistry
Gallbladder cancer (GBC) is a common malignancy of the biliary tract and is characterized by rapid progression and early metastasis. Elucidating the molecular mechanisms of GBC could help to develop better treatment strategies.