Open AccessThe Detection of Plasma Soluble Podoplanin of Patients with Breast Cancer and Its Clinical Signification
Author(s) -
Xinyi Zhu,
Mingxin Xu,
Xingpeng Zhao,
Fei Shen,
Changgeng Ruan,
Yiming Zhao
Publication year - 2020
Publication title -
cancer management and research
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.024
H-Index - 40
ISSN - 1179-1322
DOI - 10.2147/cmar.s281785
Subject(s) - podoplanin , breast cancer , medicine , cancer detection , oncology , cancer , immunohistochemistry
Podoplanin (PDPN) is a type-1 membrane sialoglycoprotein that is expressed in many cancer tumors including breast cancer; nonetheless, its roles in tumor occurrence, development, and metastasis are unclear. In this study, we aimed to investigate the clinical significance of plasma soluble PDPN (sPDPN) levels in patients with breast cancer and its significance in the diagnosis and metastasis.