Open AccessCircRNA circ_POLA2 is Upregulated in Acute Myeloid Leukemia (AML) and Promotes Cell Proliferation by Suppressing the Production of Mature miR-34a
Author(s) -
Hong Li,
Kehong Bi,
Saran Feng,
Yan Wang,
Chuansheng Zhu
Publication year - 2021
Publication title -
cancer management and research
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.024
H-Index - 40
ISSN - 1179-1322
DOI - 10.2147/cmar.s281690
Subject(s) - myeloid leukemia , downregulation and upregulation , cell growth , oncogene , cancer research , cell , leukemia , cell culture , medicine , chemistry , biology , cancer , immunology , cell cycle , gene , biochemistry , genetics
CircRNA circ_POLA2 has been reported as an oncogene in lung cancer, while its role in other malignancies is unknown. This study aimed to explore the role of circ_POLA2 in acute myeloid leukemia (AML).