Open Access<p>Whole-Brain Radiotherapy Can Improve the Survival of Patients with Multiple Brain Metastases from Non-Small Cell Lung Cancer Treated by Epidermal Growth Factor Receptor-Tyrosine Kinase Inhibitors</p>
Author(s) -
Cheng Chen,
Yan Wu,
Bao Ling Liu,
Hong Wei Wang,
Jian DuShucheng Hua,
Ju Zhou
Publication year - 2020
Publication title -
cancer management and research
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.024
H-Index - 40
ISSN - 1179-1322
DOI - 10.2147/cmar.s279096
Subject(s) - medicine , lung cancer , oncology , epidermal growth factor receptor , progression free survival , radiation therapy , tyrosine kinase inhibitor , epidermal growth factor , proportional hazards model , multivariate analysis , cancer , overall survival , receptor
To observe whether whole-brain radiotherapy (WBRT) can bring survival benefits to patients with multiple brain metastases (BM) from non-small cell lung cancer (NSCLC) treated by epidermal growth factor receptor (EGFR) tyrosine kinase inhibitor (TKI) and determine the best time for WBRT intervention.