Open Access<p>Effects of <em>Annona muricata</em> Extract on Triple-Negative Breast Cancer Cells Mediated Through EGFR Signaling</p>
Author(s) -
Heba K. Alshaeri,
Moudi M. Alasmari,
Zuhair S. Natto,
Alejandro PinoFigueroa
Publication year - 2020
Publication title -
cancer management and research
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.024
H-Index - 40
ISSN - 1179-1322
DOI - 10.2147/cmar.s278647
Subject(s) - viability assay , annona muricata , cyclin d1 , protein kinase b , mapk/erk pathway , ethyl acetate , chemistry , mtt assay , triple negative breast cancer , microbiology and biotechnology , cell cycle , cell growth , biology , cell , signal transduction , biochemistry , traditional medicine , medicine , cancer , breast cancer , genetics
To evaluate the antiproliferative activity and the mechanisms of action of Annona muricata ethyl acetate (AMEA) extract and one of its active fractions on BT-20 TNBC cells.