Open Access<p>Expression and Importance of TMED2 in Multiple Myeloma Cells</p>
Author(s) -
Xueling Ge,
Wei Jiang,
Yujie Jiang,
Xiao Lv,
Xin Liu,
Xin Wang
Publication year - 2020
Publication title -
cancer management and research
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.024
H-Index - 40
ISSN - 1179-1322
DOI - 10.2147/cmar.s278570
Subject(s) - cell cycle , transfection , cell culture , apoptosis , downregulation and upregulation , viability assay , microbiology and biotechnology , cell growth , gene silencing , small hairpin rna , biology , cell , gene expression , andrology , chemistry , gene , medicine , gene knockdown , genetics
TMED2 is a member of the transmembrane emp24 domain (Tmed)/p24 protein family, which is significantly upregulated in breast cancer, ovarian cancer and other tumour tissues. The purpose of this study was to investigate the expression of TMED2 in MM cell lines and its effect on the biological behaviour of MM cell lines.