Open AccessLncRNA NEAT1/miR-204/NUAK1 Axis is a Potential Therapeutic Target for Non-Small Cell Lung Cancer
Author(s) -
Mingming Zhao,
Linyang Ge,
Liangfeng Yang,
Haixia Zheng,
Gang Chen,
Li-An Wu,
Shao-Ming Shi,
Nan Wang,
Yan-Ping Hang
Publication year - 2020
Publication title -
cancer management and research
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.024
H-Index - 40
ISSN - 1179-1322
DOI - 10.2147/cmar.s277524
Subject(s) - cancer research , cell growth , long non coding rna , biology , lung cancer , microrna , cell , rna , medicine , gene , oncology , biochemistry
Long non-coding RNA (lncRNA) is a key part of non-coding RNA, and more and more evidence has revealed that it plays a vital role in tumors. NEAT1 is a lncRNA discovered in the early stage. However, it is still unclear whether NEAT1 and miR-204 play a regulatory role in lung cancer (LC). This research aimed to determine the biological function of NEAT1 / miR-204 in non-small cell lung cancer (NSCLC).