Open Access<p>Ropivacaine Inhibits Cell Proliferation, Migration and Invasion, Whereas Induces Oxidative Stress and Cell Apoptosis by circSCAF11/miR-145-5p Axis in Glioma</p>
Author(s) -
Danqin Yin,
Li Liu,
Zhengyuan Shi,
Lihui Zhang,
Yan Yang
Publication year - 2020
Publication title -
cancer management and research
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.024
H-Index - 40
ISSN - 1179-1322
DOI - 10.2147/cmar.s274975
Subject(s) - glioma , cell growth , apoptosis , flow cytometry , downregulation and upregulation , cancer research , chemistry , vimentin , cell , cell migration , microbiology and biotechnology , oxidative stress , carcinogenesis , biology , immunology , biochemistry , immunohistochemistry , gene
Glioma is a heterogeneous aggressive tumor. Ropivacaine, a widely used anesthetic, has been shown to repress the progression of multiple cancers, including glioma. In this study, the effects of ropivacaine on cell proliferation, migration, invasion and apoptosis in glioma were revealed.