Open AccessLINC00265/miR-4500 Axis Accelerates Acute Lymphoblastic Leukemia Progression by Enhancing STAT3 Signals
Author(s) -
Di Zhao,
Qi Xing,
Hang Song,
Yan Zhao,
Guiying Guo
Publication year - 2021
Publication title -
cancer management and research
Language(s) - Uncategorized
Resource type - Journals
SCImago Journal Rank - 1.024
H-Index - 40
ISSN - 1179-1322
DOI - 10.2147/cmar.s274590
Subject(s) - gene silencing , cancer research , cell growth , stat3 , microrna , cell culture , cell , biology , signal transduction , microbiology and biotechnology , gene , genetics
Long noncoding RNA LINC00265 or miR-4500 is involved in the pathogenesis of many cancers. However, their functions in acute lymphoblastic leukemia (ALL) remain unknown. In this study, we investigated how LINC00265 and miR-4500 regulate the malignant characteristics of ALL.