Open AccessLncRNA BLACAT1/miR-519d-3p/CREB1 Axis Mediates Proliferation, Apoptosis, Migration, Invasion, and Drug-Resistance in Colorectal Cancer Progression
Author(s) -
Rui Chen,
Siying Zhou,
Jianhui Chen,
Senbin Lin,
Feifei Ye,
Pinlu Jiang
Publication year - 2020
Publication title -
cancer management and research
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.024
H-Index - 40
ISSN - 1179-1322
DOI - 10.2147/cmar.s274447
Subject(s) - apoptosis , cancer research , colorectal cancer , flow cytometry , metastasis , western blot , cell growth , gene silencing , cancer , medicine , biology , microbiology and biotechnology , gene , genetics
Colorectal cancer (CRC) is a common severe disease around the world. The merging papers reported that long noncoding RNAs (lncRNAs) took part in the diversified pathological processes of CRC. This study aimed to uncover the role and the potential mechanism of lncRNA bladder cancer-associated transcript 1 (BLACAT1) in CRC progression.