Open AccessCircSKA3 Modulates FOXM1 to Facilitate Cell Proliferation, Migration, and Invasion While Confine Apoptosis in Medulloblastoma via miR-383-5p
Author(s) -
Xinfang Wang,
Dong Xu,
Xin Yan Pei,
Yingying Zhang,
Yuling Zhang,
Yaxing Gu,
Ying Li
Publication year - 2020
Publication title -
cancer management and research
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.024
H-Index - 40
ISSN - 1179-1322
DOI - 10.2147/cmar.s272753
Subject(s) - flow cytometry , apoptosis , cell growth , foxm1 , cell , viability assay , cell cycle , cancer research , cell migration , microrna , chemistry , medulloblastoma , oncogene , gene silencing , mtt assay , microbiology and biotechnology , biology , biochemistry , gene
Medulloblastoma (MB) is the most common malignant brain tumor during childhood. Circular RNA (circSKA3) was identified to function as an oncogene in MB. However, the mechanism of circSKA3 in MB remains unclear.