Open AccessLncRNA RUNX1-IT1 is Downregulated in Endometrial Cancer and Binds to miR-21 Precursor to Suppress Its Maturation
Author(s) -
Liang Mao,
Hongbo Wang,
Cong Liu,
Lei Tao,
Jie Min
Publication year - 2020
Publication title -
cancer management and research
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.024
H-Index - 40
ISSN - 1179-1322
DOI - 10.2147/cmar.s272165
Subject(s) - runx1 , cell growth , endometrial cancer , cancer research , downregulation and upregulation , chemistry , cancer cell , cancer , biology , microbiology and biotechnology , transcription factor , gene , biochemistry , genetics
RUNX1-IT1 suppresses colorectal cancer and liver cancer, while its role in other cancers is unknown. This study was performed to investigate the role of RUNX1-IT1 in endometrial cancer (EC).